Last month we mentioned the challenges of studying blue whales in a laboratory setting. If we want to know what a particular gene or protein does in an animal that large, we often have to rely on inference based on what a comparable gene or protein does in an animal we can study more readily like a mouse. And how do we know which protein is comparable--or homologous, to use the more technical term? Typically the search for homologous proteins starts with a sequence similarity scan, a check of an entire library of … [Read more...] about Science Corner: Finding the Proteins of Theseus
Science Corner: Don’t It Make My Blue Whale Big
I was fortunate to grow up within visiting distance of the American Museum of Natural History in New York City. One item stands out in my memories from periodic visits: the blue whale. Not a live one, of course; it's a museum, not an aquarium. Even as an inert model, the blue whale was striking to little-boy-me--which is saying something since it shares a home with numerous dinosaur skeletons. Of course, that cohabitation only helps to underline just how much bigger blue whales are than even the biggest dinosaurs or … [Read more...] about Science Corner: Don’t It Make My Blue Whale Big
Science Corner: New Genes for a New You
For the new year, let's look at where new genes come from. Many genes around today have pedigrees going back billions of years. Humans can find analogues of most of their genes in chimpanzees and other primates, suggesting our common ancestor millions of years ago had comparable genes. At the same time, many species including humans have genes found in no other species. As with so many things--to-do lists, spreadsheets, computer code, building plans--there are two main ways to get new ones: copy and modify something … [Read more...] about Science Corner: New Genes for a New You
Science Corner: The Case of a Curious Christmas
Among the holidays widely observed in the United States, Christmas strikes me as the one most concerned with curiosity. Several Christmas songs are posed as questions: "What Child is This?" and "Do You See What I See?" and "Mary, Did You Know?" OK, that last one has a real 'more of a comment than a question' energy, but still. There are the magi on a quest of discovery. There is the mystery and anticipation of a wrapped gift. And so I thought the science of curiosity would be an apt topic for this Advent season. … [Read more...] about Science Corner: The Case of a Curious Christmas
Science Corner: Who is My Neighbor?
By the time you read this, the United States will be learning the outcomes of midterm elections. Obviously I don't know the results to comment. Regardless of the outcome, though, I think it is likely we will continue to hear about the partisan divide or variations thereof. And that is a topic which science can offer some insight into, specifically the impact of social media on polarization--specifically, our increased sorting into homogeneous groups with little in common between them. If you suspect social media isn't … [Read more...] about Science Corner: Who is My Neighbor?